Progress on indium and barium single ion optical frequency standards

We report progress on 115In+ and 137Ba+ single ion optical frequency standards using all solid-state sources. Both are free from quadrupole field shifts and together enable a search for drift in fundamental constants.Comment: 2 pages, 1 figure, submitted to IEEE/LEOS Summer 2005 Topicals conference proceeding

Search for domain wall dark matter with atomic clocks on board global positioning system satellites

Cosmological observations indicate that 85% of all matter in the Universe is dark matter (DM), yet its microscopic composition remains a mystery. One hypothesis is that DM arises from ultralight quantum fields that form macroscopic objects such as topological defects. Here we use GPS as a ~ 50,000 km aperture DM detector to search for such defects in the form of domain walls. GPS navigation relies on precision timing signals furnished by atomic clocks hosted on board GPS satellites. As the Earth moves through the galactic DM halo, interactions with topological defects could cause atomic clock glitches that propagate through the GPS satellite constellation at galactic velocities ~ 300 km/s. Mining 16 years of archival GPS data, we find no evidence for DM in the form of domain walls at our current sensitivity level. This allows us to improve the limits on certain quadratic scalar couplings of domain wall DM to standard model particles by several orders of magnitude.Comment: 7 pages (main text), and 12 pages for Supplementary Information. v3: Update titl

Saving Tons at the Register

Duct losses have a significant effect on the efficiency of delivering space cooling to U.S. homes. This effect is especially dramatic during peak demand periods where half of the cooling equipment's output can be wasted. Improving the efficiency of a duct system can save energy, but can also allow for downsizing of cooling equipment without sacrificing comfort conditions. Comfort, and hence occupant acceptability, is determined not only by steady-state temperatures, but by how long it takes to pull down the temperature during cooling start-up, such as when the occupants come home on a hot summer afternoon. Thus the delivered tons of cooling at the register during start-up conditions are critical to customer acceptance of equipment downsizing strategies. We have developed a simulation technique which takes into account such things as weather, heat-transfer (including hot attic conditions), airflow, duct tightness, duct location and insulation, and cooling equipment performance to determine the net tons of cooling delivered to occupied space. Capacity at the register has been developed as an improvement over equipment tonnage as a system sizing measure. We use this concept to demonstrate that improved ducts and better system installation is as important as equipment size, with analysis of pull-down capability as a proxy for comfort. The simulations indicate that an improved system installation including tight ducts can eliminate the need for almost a ton of rated equipment capacity in a typical new 2,000 square foot house in Sacramento, California. Our results have also shown that a good duct system can reduce capacity requirements and still provide equivalent cooling at start-up and at peak conditions

Improving Parental Engagement for Latino Youths\u27 Educational Success: Lessons from Juntos Oregon

Research has shown that more efforts are needed to increase high school completion and postsecondary enrollment among Latino youths. However, little is known regarding efforts that engage both Latino youths and their parents. To address this gap, we surveyed Juntos Oregon participants to examine the school and community context Latino youths and their families face in the educational journey and identify effects of the Juntos program. Results showed that in a context of persistent discrimination and unfair treatment, Juntos workshops increased the sense of school and community connectedness among Latino parents. Increases in academic planning and motivation occurred as well. Extension may increase its educational impact by strengthening connections and promoting engagement between schools and Latino families

Prospectus, November 17, 1982

REVIEW BOARD VOTES TO DISMISS STUGO SENATOR; News Digest; We focus on Gibson City; Education necessary to prevent devastation; Election will not solve problems; Student concerned about car parking; \u27Humorist\u27 saga may end; Smokers face higher prices, risk; Parkland club notes: German Club, PMA, BSA; Day set aside to kick habit; Parkland students honored; Urbana High plans dinner; C-U Happenings; Mr. Roberts to speak at P.C.; Little snow seen for November; \u27Valspeak\u27 thought to be less than awesome; You too, can be like, incoherent; Gallery has photo exhibit; Ideas needed; Places and faces in Gibson City; The voodoo chile lives; Petty talent on upswing; Palin provides irreverent relevance; B movies receive star treatment; Abba member goes solo; Second City first rate; Tour the galaxy without panic; Classified; Skylines; Family weekend set for sports; Sports Shorts; \u27Will the big men bring home the bacon\u27?; Slow Samhttps://spark.parkland.edu/prospectus_1982/1004/thumbnail.jp

The Grizzly, March 23, 1999

For 27 Ursinus Students, Spring Break is No Day at the Beach • Former CIA Member to Speak on U.S. Intelligence • French Conducts Meistersingers Concert • A New Reimert for a New Season • UC Students Check Out Hot Internet Sites • Do You Remember Last Wednesday? • Opinion: Warning This Article has Been Censored; A Cruel Second; Cash Equivalency Controversy Revisited • Back in the Swing of Things: UC Baseball Report • Softball Evens Record at 7-7 • Gymnastics Holds Own at Nationals • UC Lax Drops First Two • Men\u27s Tennis Team Splits Matcheshttps://digitalcommons.ursinus.edu/grizzlynews/1437/thumbnail.jp

Transmembrane stem cell factor protein therapeutics enhance revascularization in ischemia without mast cell activation

Stem cell factor (SCF) is a cytokine that regulates hematopoiesis and other biological processes. While clinical treatments using SCF would be highly beneficial, these have been limited by toxicity related to mast cell activation. Transmembrane SCF (tmSCF) has differential activity from soluble SCF and has not been explored as a therapeutic agent. We created novel therapeutics using tmSCF embedded in proteoliposomes or lipid nanodiscs. Mouse models of anaphylaxis and ischemia revealed the tmSCF-based therapies did not activate mast cells and improved the revascularization in the ischemic hind limb. Proteoliposomal tmSCF preferentially acted on endothelial cells to induce angiogenesis while tmSCF nanodiscs had greater activity in inducing stem cell mobilization and recruitment to the site of injury. The type of lipid nanocarrier used altered the relative cellular uptake pathways and signaling in a cell type dependent manner. Overall, we found that tmSCF-based therapies can provide therapeutic benefits without off target effects